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FNP Question of the Day

Sharpen your family nurse practitioner prep with a fresh FNP practice question, updated daily.

10 September 2026 Share on X Share on LinkedIn
Subject: Musculoskeletal CareMusculoskeletal CareLow back pain evaluation and red-flag screening
Question
During a telehealth visit, Mr. Henderson, an 80-year-old male who lives independently, presents with a new complaint of low back pain. He describes the pain as a constant, dull ache located in his lumbosacral region, which occasionally radiates into his right buttock. The pain started approximately two weeks ago without a precipitating injury, has progressively worsened, and is now rated 6/10 at its worst, aggravated by movement and prolonged standing. He reports difficulty sleeping through the night due to discomfort.

His medical history includes well-controlled essential hypertension, managed with lisinopril, and mild chronic kidney disease (CKD) Stage 2 with an eGFR around 70 mL/min/1.73m^2 from labs three months prior. He denies any fever, chills, bowel or bladder incontinence, saddle anesthesia, or lower extremity weakness. However, he casually mentions he has unintentionally lost about five pounds over the past three months, attributing it to a 'reduced appetite.' He takes over-the-counter acetaminophen for occasional headaches but uses celecoxib 200 mg daily for 5-7 days when his knee osteoarthritis flares. He denies any recent trauma or falls.

Considering Mr. Henderson's presentation, age, comorbidities, and the red-flag finding, which of the following is the most appropriate initial pharmacologic management plan?

Select an Answer
Rationale:
The most appropriate initial pharmacologic management involves acetaminophen at a reduced maximum daily dose due to the patient's age and mild chronic kidney disease. Acetaminophen is the first-line analgesic for mild to moderate musculoskeletal pain and has the lowest risk of adverse effects compared to NSAIDs or opioids in this population. Concurrently, the unintentional weight loss is a significant red flag for serious underlying pathology, such as malignancy, infection, or systemic inflammatory disease, necessitating an urgent in-person evaluation to facilitate comprehensive physical examination, laboratory workup, and appropriate advanced imaging (e.g., MRI) rather than just an X-ray.

Prescribing celecoxib (an NSAID) is relatively contraindicated due to his CKD Stage 2 and advanced age, as NSAIDs can worsen renal function and increase cardiovascular risk. Increasing acetaminophen to 1000 mg every 6 hours exceeds the recommended maximum daily dose for an 80-year-old with CKD (typically not exceeding 2-3g/day) and fails to address the urgency of the red flag. Prescribing tramadol (an opioid) is generally not first-line for acute low back pain, especially in an elderly patient, due to risks of sedation, constipation, falls, and potential for dependence. A lumbar spine X-ray is insufficient to rule out serious conditions suggested by the red flag; an MRI would be more appropriate for evaluating soft tissue, infection, or malignancy.

9 September 2026 Share on X Share on LinkedIn
Subject: Endocrine and Metabolic CareEndocrine and Metabolic CareType 2 diabetes diagnosis and management
Question
During an afternoon shift at a college health clinic, a 45-year-old adjunct professor presents complaining of feeling "off" for the past two weeks. He reports increased thirst, frequent urination, and generalized fatigue. He also mentions a recent, noticeable blurring of his vision, making it difficult to read lecture notes. He has no significant past medical history, states he rarely sees a physician, and his last physical was over five years ago. He admits to a sedentary lifestyle and a diet rich in processed foods, noting a gradual weight gain over the past several years.

On examination, his vital signs are: BP 142/88 mmHg, HR 92 bpm, RR 18 bpm, Temp 98.6°F (37.0°C), SpO2 99% on room air. He appears moderately overweight, with a BMI of 31 kg/m². His mucous membranes are tacky. A point-of-care fingerstick blood glucose reads "HIGH" (>500 mg/dL). A urine dipstick reveals 4+ glucose and moderate ketones.

Considering this patient's presentation, which of the following is the most immediate and critical management priority?

Select an Answer
Rationale:
The patient's presentation with profound hyperglycemia (>500 mg/dL), polyuria, polydipsia, fatigue, blurred vision, tacky mucous membranes (suggesting dehydration), and crucially, moderate ketones in the urine, points to a severe acute metabolic decompensation such as Diabetic Ketoacidosis (DKA) or a severe hyperosmolar state with ketosis. While DKA is classically associated with Type 1 diabetes, it can occur in Type 2 diabetes, often termed "ketosis-prone Type 2 diabetes."

These findings constitute a red flag requiring urgent escalation beyond primary care management. Attempting to manage this level of hyperglycemia and potential acidosis/dehydration in an outpatient setting is unsafe. The patient requires immediate transfer to an emergency department for intravenous fluid resuscitation, insulin infusion, electrolyte monitoring and replacement, and definitive diagnosis of the underlying acute condition. The other options represent appropriate steps for routine diagnosis and management of Type 2 diabetes, but they are not the most immediate and critical priorities for a patient presenting with an acute, life-threatening metabolic crisis.

8 September 2026 Share on X Share on LinkedIn
Subject: Pediatric Primary CarePediatric Primary CareRoutine childhood immunization schedules
Question
A 6-year-old male presents for his annual wellness visit. His mother expresses concerns about school entry requirements regarding immunizations. Review of the state immunization registry shows the child is up-to-date on DTaP (4 doses), IPV (3 doses), MMR (1 dose), and has no record of Varicella vaccine administration. The mother reports, "He definitely had the chickenpox when he was about three years old, but I don't remember if the doctor ever officially diagnosed it. It was a mild case, just a few spots."

The child's growth parameters are at the 50th percentile for age, vital signs are stable, and the physical examination is unremarkable. There are no signs of acute illness, and the child has no known chronic medical conditions or immune compromise.

Considering the mother's report and the missing immunization record, what is the most appropriate next diagnostic step in managing this child's immunization status?

Select an Answer
Rationale:
According to the Advisory Committee on Immunization Practices (ACIP) guidelines, acceptable evidence of immunity to varicella for children 12 months through 12 years of age includes documentation of 2 doses of varicella vaccine; diagnosis of varicella by a healthcare provider or verified by a parent or guardian who has seen the characteristic rash; or, laboratory evidence of immunity. In this scenario, the mother's description of a "mild case, just a few spots" is atypical for a classic varicella rash and therefore is not considered a reliable history sufficient to confirm immunity. Without reliable parental history or prior vaccine documentation, the child is presumed susceptible.

While administering the vaccine is often the next step in managing a susceptible child, the question specifically asks for the most appropriate *diagnostic step*. Obtaining a VZV IgG antibody titer is the definitive diagnostic test to confirm immunity in cases where clinical history is unreliable or documentation is absent. This approach allows for confirmation of immunity before administering a potentially unnecessary vaccine dose. Requesting prior records is a good initial step, but the mother's statement about an unconfirmed diagnosis suggests those records may not yield definitive evidence. Advising that an unreliable parental report is sufficient for immunity is incorrect based on ACIP guidelines.

7 September 2026 Share on X Share on LinkedIn
Subject: Pharmacology and PrescribingPharmacology and PrescribingOutpatient antibiotic selection principles
Question
During a new patient intake visit, you are reviewing the medical history of an 80-year-old male who lives independently and maintains an active lifestyle. He reports an unremarkable past medical history except for experiencing "a few bladder infections over the past several years" for which he received oral antibiotics, though he cannot recall the specific medications or the duration of treatment. He denies any current urinary symptoms, fever, or flank pain.

His vital signs are stable: BP 130/78 mmHg, HR 72 bpm, RR 16 bpm, Temp 98.4°F (36.9°C), O2 Sat 98% on room air. Physical exam is within normal limits for his age. As part of establishing a comprehensive preventive care plan, you are considering key discussions regarding his past antibiotic use and future infection prevention.

Considering his age and history, which of the following is the most appropriate initial screening and prevention strategy to discuss with this patient regarding outpatient antibiotic selection principles?

Select an Answer
Rationale:
In an 80-year-old male presenting for a new patient intake with a history of "bladder infections" but no current symptoms, the most critical screening and prevention strategy related to outpatient antibiotic selection principles is to address asymptomatic bacteriuria (ASB). Older adults, especially women but also men, frequently have ASB, which does not require antibiotic treatment unless specific symptomatic conditions are present (e.g., prior to urological procedures). The patient's history of past "bladder infections" without recalling specific symptoms raises a red flag for potential past treatment of ASB. This discussion serves as a screening tool for the patient's understanding of urinary tract infections and as a preventative measure against future inappropriate antibiotic prescribing.

Treating ASB leads to unnecessary antibiotic exposure, increased risk of adverse effects (e.g., Clostridioides difficile infection), and promotion of antibiotic resistance without providing clinical benefit. Therefore, counseling on the appropriate management of ASB directly addresses a core principle of antibiotic stewardship and selection in this demographic. While other options like ensuring appropriate immunizations, completing antibiotic courses, and discussing non-pharmacological UTI prevention are important, they do not as directly align with 'screening and prevention strategy regarding outpatient antibiotic selection principles' for this specific patient presentation as the discussion on ASB, which guides *when to select* (or, more importantly, *when not to select*) an antibiotic for a common clinical scenario.

6 September 2026 Share on X Share on LinkedIn
Subject: Genitourinary and Renal CareGenitourinary and Renal CareBenign prostatic hyperplasia management
Question
A 34-year-old patient presents for her annual wellness visit. She is currently at 28 weeks gestation and reports a recent onset of increased urinary frequency and urgency, accompanied by nocturia. She notes these symptoms are reminiscent of the lower urinary tract symptoms her father experienced prior to his diagnosis of benign prostatic hyperplasia.

Her vital signs are stable: blood pressure 110/70 mmHg, pulse 78 bpm, respiratory rate 16 breaths/min, temperature 98.6°F (37°C). A comprehensive physical examination, including an external genitourinary assessment, reveals no remarkable findings, and fundal height is appropriate for gestational age.

Considering this patient's presentation and medical history, which of the following is the most appropriate next diagnostic step?

Select an Answer
Rationale:
The patient is a 34-year-old pregnant female. Benign prostatic hyperplasia (BPH) is a condition affecting the prostate gland, which is a male anatomical structure. Therefore, it is physiologically impossible for a pregnant female to develop BPH. The patient's reported symptoms of increased urinary frequency, urgency, and nocturia in pregnancy are common and could indicate a urinary tract infection (UTI) or asymptomatic bacteriuria (ASB), which require screening and treatment during pregnancy due to the risk of pyelonephritis and adverse pregnancy outcomes. A urine culture and sensitivity test is the most appropriate diagnostic step to identify the presence and type of bacteria, guiding effective treatment.

The options of prostate-specific antigen (PSA) measurement, digital rectal examination, and transrectal ultrasound of the prostate are diagnostic tests specifically utilized for the evaluation of prostate conditions in males. Ordering any of these tests for a pregnant female would demonstrate a critical misunderstanding of basic human anatomy and physiology, as well as the diagnostic approach to urinary symptoms in pregnancy. While the patient mentions her father's BPH, the FNP must recognize that this diagnosis is irrelevant to her personal symptoms and instead focus on appropriate female-specific diagnostics for her presentation.